Hypothesis: Why Different Types of SDH Gene Variants Cause Divergent Tumor Phenotypes

Despite two decades of paraganglioma-pheochromocytoma research, the fundamental question of how the different succinate dehydrogenase (SDH)-related tumor phenotypes are initiated has remained unanswered. Here, we discuss two possible scenarios by which missense (hypomorphic alleles) or truncating (n...

Descripción completa

Detalles Bibliográficos
Autores principales: Bayley, Jean-Pierre, Devilee, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222429/
https://www.ncbi.nlm.nih.gov/pubmed/35741787
http://dx.doi.org/10.3390/genes13061025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222429/
https://www.ncbi.nlm.nih.gov/pubmed/35741787
http://dx.doi.org/10.3390/genes13061025

Ejemplares similares