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Hypothesis: Why Different Types of SDH Gene Variants Cause Divergent Tumor Phenotypes
Despite two decades of paraganglioma-pheochromocytoma research, the fundamental question of how the different succinate dehydrogenase (SDH)-related tumor phenotypes are initiated has remained unanswered. Here, we discuss two possible scenarios by which missense (hypomorphic alleles) or truncating (n...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222429/ https://www.ncbi.nlm.nih.gov/pubmed/35741787 http://dx.doi.org/10.3390/genes13061025 |