Exploring the Potential of Symmetric Exon Deletion to Treat Non-Ischemic Dilated Cardiomyopathy by Removing Frameshift Mutations in TTN

Non-ischemic dilated cardiomyopathy (DCM) is one of the most frequent pathologies requiring cardiac transplants. Even though the etiology of this disease is complex, frameshift mutations in the giant sarcomeric protein Titin could explain up to 25% of the familial and 18% of the sporadic cases of DC...

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Detalles Bibliográficos
Autores principales: Rodriguez-Polo, Ignacio, Behr, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222585/
https://www.ncbi.nlm.nih.gov/pubmed/35741855
http://dx.doi.org/10.3390/genes13061093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222585/
https://www.ncbi.nlm.nih.gov/pubmed/35741855
http://dx.doi.org/10.3390/genes13061093

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