Intranasal Delivery of Darunavir-Loaded Mucoadhesive In Situ Gel: Experimental Design, In Vitro Evaluation, and Pharmacokinetic Studies

The clinical efficacy of antiretroviral therapy in NeuroAIDS is primarily limited by the low perfusion of the drug to the brain. The objective of the current investigation was to design and develop an in situ mucoadhesive gel loaded with darunavir to assess the feasibility of brain targeting through...

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Detalles Bibliográficos
Autores principales: Nair, Anroop B., Chaudhary, Sunita, Shah, Hiral, Jacob, Shery, Mewada, Vivek, Shinu, Pottathil, Aldhubiab, Bandar, Sreeharsha, Nagaraja, Venugopala, Katharigatta N., Attimarad, Mahesh, Shah, Jigar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223067/
https://www.ncbi.nlm.nih.gov/pubmed/35735686
http://dx.doi.org/10.3390/gels8060342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223067/
https://www.ncbi.nlm.nih.gov/pubmed/35735686
http://dx.doi.org/10.3390/gels8060342

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