Cargando…

MarZIC: A Marginal Mediation Model for Zero-Inflated Compositional Mediators with Applications to Microbiome Data

Background: The human microbiome can contribute to pathogeneses of many complex diseases by mediating disease-leading causal pathways. However, standard mediation analysis methods are not adequate to analyze the microbiome as a mediator due to the excessive number of zero-valued sequencing reads in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Quran, O’Malley, James, Datta, Susmita, Gharaibeh, Raad Z., Jobin, Christian, Karagas, Margaret R., Coker, Modupe O., Hoen, Anne G., Christensen, Brock C., Madan, Juliette C., Li, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223163/ https://www.ncbi.nlm.nih.gov/pubmed/35741811 http://dx.doi.org/10.3390/genes13061049

Ejemplares similares

Identification of microbial interaction network: zero-inflated latent Ising model based approach
por: Zhou, Jie, et al.
Publicado: (2020)

Expression of the zic1, zic2, zic3, and zic4 genes in early chick embryos
por: McMahon, Ariel R, et al.
Publicado: (2010)

Structural zeroes and zero-inflated models
por: HE, Hua, et al.
Publicado: (2014)

Associations of maternal pre-pregnancy BMI and gestational weight gain with the infant gut microbiome differ according to delivery mode.
por: Singh, Sirtaj B, et al.
Publicado: (2019)

A comparison of zero-inflated and hurdle models for modeling zero-inflated count data
por: Feng, Cindy Xin
Publicado: (2021)

Reliability of stool microbiome methods for DNA yields and sequencing among infants and young children
por: Antosca, Katherine, et al.
Publicado: (2020)

On the equivalence of one‐inflated zero‐truncated and zero‐truncated one‐inflated count data likelihoods
por: Böhning, Dankmar
Publicado: (2022)

Association of Cesarean Delivery and Formula Supplementation with the Stool Metabolome of 6-Week-Old Infants
por: Hoen, Anne G., et al.
Publicado: (2021)

Microbiota and cancer immunotherapy: in search of microbial signals
por: Gharaibeh, Raad Z, et al.
Publicado: (2019)

Metagenomic analysis reveals associations between salivary microbiota and body composition in early childhood
por: Coker, Modupe O., et al.
Publicado: (2022)

Modeling zero inflation is not necessary for spatial transcriptomics
por: Zhao, Peiyao, et al.
Publicado: (2022)

Bayesian clustering of multiple zero-inflated outcomes
por: Franzolini, Beatrice, et al.
Publicado: (2023)

Infant Feeding Alters the Longitudinal Impact of Birth Mode on the Development of the Gut Microbiota in the First Year of Life
por: Coker, Modupe O., et al.
Publicado: (2021)

Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy
por: Hopfner, Franziska, et al.
Publicado: (2022)

The infant gut resistome is associated with E. coli and early-life exposures
por: Lebeaux, Rebecca M., et al.
Publicado: (2021)

Compositional zero-inflated network estimation for microbiome data
por: Ha, Min Jin, et al.
Publicado: (2020)

A novel conserved enhancer at zebrafish zic3 and zic6 loci drives neural expression
por: Minhas, Rashid, et al.
Publicado: (2019)

Zic Family Member 2 (ZIC2): a Potential Diagnostic and Prognostic Biomarker for Pan-Cancer
por: Lv, Zhengtong, et al.
Publicado: (2021)

Evaluation of negative binomial and zero-inflated negative binomial models for the analysis of zero-inflated count data: application to the telemedicine for children with medical complexity trial
por: Lee, Kyung Hyun, et al.
Publicado: (2023)

Zic2 hypomorphic mutant mice as a schizophrenia model and ZIC2 mutations identified in schizophrenia patients
por: Hatayama, Minoru, et al.
Publicado: (2011)

Reaching High Altitudes on Mars with an Inflatable Hypersonic Drag Balloon (Ballute)
por: Griebel, Hannes
Publicado: (2010)

Assessment and Selection of Competing Models for Zero-Inflated Microbiome Data
por: Xu, Lizhen, et al.
Publicado: (2015)

Zero‐inflated count distributions for capture–mark–reencounter data
por: Riecke, Thomas V., et al.
Publicado: (2022)

Modeling road accident fatalities with underdispersion and zero-inflated counts
por: Simmachan, Teerawat, et al.
Publicado: (2022)

The Developing Microbiome From Birth to 3 Years: The Gut-Brain Axis and Neurodevelopmental Outcomes
por: Laue, Hannah E., et al.
Publicado: (2022)

Sex-specific associations of infants’ gut microbiome with arsenic exposure in a US population
por: Hoen, Anne G., et al.
Publicado: (2018)

Human presence impacts fungal diversity of inflated lunar/Mars analog habitat
por: Blachowicz, A., et al.
Publicado: (2017)

Zero inflated Poisson and negative binomial regression models: application in education
por: Salehi, Masoud, et al.
Publicado: (2015)

Ordinal regression models for zero-inflated and/or over-dispersed count data
por: Valle, Denis, et al.
Publicado: (2019)

Zero-Inflated gaussian mixed models for analyzing longitudinal microbiome data
por: Zhang, Xinyan, et al.
Publicado: (2020)

A Zero-Inflated Latent Dirichlet Allocation Model for Microbiome Studies
por: Deek, Rebecca A., et al.
Publicado: (2021)

Monitoring the Zero-Inflated Time Series Model of Counts with Random Coefficient
por: Li, Cong, et al.
Publicado: (2021)

Evaluation of robust outlier detection methods for zero-inflated complex data
por: Templ, M., et al.
Publicado: (2019)

Zero-Inflated Time Series Modelling of COVID-19 Deaths in Ghana
por: Tawiah, Kassim, et al.
Publicado: (2021)

Modeling zero inflation and overdispersion in provisional Covid-19 death counts
por: Effiong, Andem, et al.
Publicado: (2022)

Impact of antibiotics on off-target infant gut microbiota and resistance genes in cohort studies
por: Lebeaux, Rebecca M., et al.
Publicado: (2022)

Changing Faces of Transcriptional Regulation Reflected by Zic3
por: Winata, Cecilia Lanny, et al.
Publicado: (2015)

An Evolutionarily Conserved Mesodermal Enhancer in Vertebrate Zic3
por: Odaka, Yuri S., et al.
Publicado: (2018)

Transcriptional expression of ZICs as an independent indicator of survival in gliomas
por: Han, Zhaocheng, et al.
Publicado: (2021)

Application of Zero-Inflated Poisson Mixed Models in Prognostic Factors of Hepatitis C
por: Akbarzadeh Baghban, Alireza, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_pgbkho2l5nmcu31uqkkfiis62h