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Polygenic Models Partially Predict Muscle Size and Strength but Not Low Muscle Mass in Older Women

Background: Heritability explains 45-82% of muscle mass and strength variation, yet polygenic models for muscle phenotypes in older women are scarce. Therefore, the objective of the present study was to (1) assess if total genotype predisposition score (GPS(TOTAL)) for a set of polymorphisms differe...

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Detalles Bibliográficos
Autores principales: Khanal, Praval, Morse, Christopher I., He, Lingxiao, Herbert, Adam J., Onambélé-Pearson, Gladys L., Degens, Hans, Thomis, Martine, Williams, Alun G., Stebbings, Georgina K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223182/
https://www.ncbi.nlm.nih.gov/pubmed/35741744
http://dx.doi.org/10.3390/genes13060982