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A small molecule that disrupts S. Typhimurium membrane voltage without cell lysis reduces bacterial colonization of mice
As pathogenic bacteria become increasingly resistant to antibiotics, antimicrobials with mechanisms of action distinct from current clinical antibiotics are needed. Gram-negative bacteria pose a particular problem because they defend themselves against chemicals with a minimally permeable outer memb...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223311/ https://www.ncbi.nlm.nih.gov/pubmed/35687608 http://dx.doi.org/10.1371/journal.ppat.1010606 |