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A small molecule that disrupts S. Typhimurium membrane voltage without cell lysis reduces bacterial colonization of mice

As pathogenic bacteria become increasingly resistant to antibiotics, antimicrobials with mechanisms of action distinct from current clinical antibiotics are needed. Gram-negative bacteria pose a particular problem because they defend themselves against chemicals with a minimally permeable outer memb...

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Detalles Bibliográficos
Autores principales: Dombach, Jamie L., Quintana, Joaquin LJ, Allgood, Samual C., Nagy, Toni A., Gustafson, Daniel L., Detweiler, Corrella S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223311/
https://www.ncbi.nlm.nih.gov/pubmed/35687608
http://dx.doi.org/10.1371/journal.ppat.1010606