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Reconstructing the history of founder events using genome-wide patterns of allele sharing across individuals

Founder events play a critical role in shaping genetic diversity, fitness and disease risk in a population. Yet our understanding of the prevalence and distribution of founder events in humans and other species remains incomplete, as most existing methods require large sample sizes or phased genomes...

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Detalles Bibliográficos
Autores principales: Tournebize, Rémi, Chu, Gillian, Moorjani, Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223333/
https://www.ncbi.nlm.nih.gov/pubmed/35737729
http://dx.doi.org/10.1371/journal.pgen.1010243