Synthesis, In Vitro and In Silico Analysis of New Oleanolic Acid and Lupeol Derivatives against Leukemia Cell Lines: Involvement of the NF-κB Pathway †

Oleanolic acid (OA) and Lupeol (LU) belong to the class of natural triterpenes and are endowed with a wide range of biological activities, including cytotoxicity toward several cancer cell lines. In this context, we investigated a set of compounds obtained from the two natural precursors for the cyt...

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Detalles Bibliográficos
Autores principales: Fontana, Gianfranco, Badalamenti, Natale, Bruno, Maurizio, Castiglione, Davide, Notarbartolo, Monica, Poma, Paola, Spinella, Alberto, Tutone, Marco, Labbozzetta, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223357/
https://www.ncbi.nlm.nih.gov/pubmed/35743037
http://dx.doi.org/10.3390/ijms23126594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223357/
https://www.ncbi.nlm.nih.gov/pubmed/35743037
http://dx.doi.org/10.3390/ijms23126594

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