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Overexpression of p-4EBP1 associates with p-eIF4E and predicts poor prognosis for non-small cell lung cancer patients with resection

Eukaryotic initiation factor 4E (eIF4E) and its phosphorylated form (p-eIF4E) play a crucial role in the protein synthesis, both are under regulation of eIF4E-binding protein 1 (4EBP1) and mitogen-activated protein kinase (MAPK)-interacting kinases (MNKs). This study aims to explore the potential pr...

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Detalles Bibliográficos
Autores principales: Tang, Yaoxiang, Luo, Jiadi, Yang, Yang, Liu, Sile, Zheng, Hongmei, Zhan, Yuting, Fan, Songqing, Wen, Qiuyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223369/
https://www.ncbi.nlm.nih.gov/pubmed/35737644
http://dx.doi.org/10.1371/journal.pone.0265465