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Sex-specific variation in R-loop formation in Drosophila melanogaster

R-loops are three-stranded nucleotide structures consisting of a DNA:RNA hybrid and a displaced ssDNA non-template strand. Previous work suggests that R-loop formation is primarily determined by the thermodynamics of DNA:RNA binding, which are governed by base composition (e.g., GC skew) and transcr...

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Detalles Bibliográficos
Autores principales: Stanek, Timothy J., Cao, Weihuan, Mehra, Rohan M, Ellison, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223372/
https://www.ncbi.nlm.nih.gov/pubmed/35687614
http://dx.doi.org/10.1371/journal.pgen.1010268