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The Combined Inactivation of Intestinal and Hepatic ZIP14 Exacerbates Manganese Overload in Mice
ZIP14 is a newly identified manganese transporter with high levels of expression in the small intestine and the liver. Loss-of-function mutations in ZIP14 can lead to systemic manganese overload, which primarily affects the central nervous system, causing neurological disorders. To elucidate the rol...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223378/ https://www.ncbi.nlm.nih.gov/pubmed/35742937 http://dx.doi.org/10.3390/ijms23126495 |