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The Combined Inactivation of Intestinal and Hepatic ZIP14 Exacerbates Manganese Overload in Mice

ZIP14 is a newly identified manganese transporter with high levels of expression in the small intestine and the liver. Loss-of-function mutations in ZIP14 can lead to systemic manganese overload, which primarily affects the central nervous system, causing neurological disorders. To elucidate the rol...

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Detalles Bibliográficos
Autores principales: Fung, Caitlin K., Zhao, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223378/
https://www.ncbi.nlm.nih.gov/pubmed/35742937
http://dx.doi.org/10.3390/ijms23126495