Divergent signaling requirements of dSARM in injury-induced degeneration and developmental glial phagocytosis

Elucidating signal transduction mechanisms of innate immune pathways is essential to defining how they elicit distinct cellular responses. Toll-like receptors (TLR) signal through their cytoplasmic TIR domains which bind other TIR domain-containing adaptors. dSARM/SARM1 is one such TIR domain adapto...

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Detalles Bibliográficos
Autores principales: Herrmann, Kelsey A., Liu, Yizhou, Llobet-Rosell, Arnau, McLaughlin, Colleen N., Neukomm, Lukas J., Coutinho-Budd, Jaeda C., Broihier, Heather T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223396/
https://www.ncbi.nlm.nih.gov/pubmed/35737721
http://dx.doi.org/10.1371/journal.pgen.1010257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223396/
https://www.ncbi.nlm.nih.gov/pubmed/35737721
http://dx.doi.org/10.1371/journal.pgen.1010257

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