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Divergent signaling requirements of dSARM in injury-induced degeneration and developmental glial phagocytosis
Elucidating signal transduction mechanisms of innate immune pathways is essential to defining how they elicit distinct cellular responses. Toll-like receptors (TLR) signal through their cytoplasmic TIR domains which bind other TIR domain-containing adaptors. dSARM/SARM1 is one such TIR domain adapto...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223396/ https://www.ncbi.nlm.nih.gov/pubmed/35737721 http://dx.doi.org/10.1371/journal.pgen.1010257 |