EST79232 and EST79376, Two Novel Sigma-1 Receptor Ligands, Exert Neuroprotection on Models of Motoneuron Degeneration

Motor neuron diseases (MNDs) include sporadic and hereditary neurological disorders characterized by progressive degeneration of motor neurons (MNs). Sigma-1 receptor (Sig-1R) is a protein enriched in MNs, and mutations on its gene lead to various types of MND. Previous studies have suggested that S...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaja-Capdevila, Núria, Hernández, Neus, Yeste, Sandra, Reinoso, Raquel F., Burgueño, Javier, Montero, Ana, Merlos, Manuel, Vela, José M., Herrando-Grabulosa, Mireia, Navarro, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223397/
https://www.ncbi.nlm.nih.gov/pubmed/35743175
http://dx.doi.org/10.3390/ijms23126737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223397/
https://www.ncbi.nlm.nih.gov/pubmed/35743175
http://dx.doi.org/10.3390/ijms23126737

Ejemplares similares