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Hypercholesterolemia Negatively Regulates P2X7-Induced Cellular Function in CD4(+) and CD8(+) T-Cell Subsets from B6 Mice Fed a High-Fat Diet

We have previously showed that plasma membrane cholesterol and GM1 ganglioside content are responsible for the opposite sensitivity of mouse leukemic T cells to ATP. We also reported that the sensitivity of CD4(+) and CD8(+) T cells to ATP depends on their stage of differentiation. Here, we show tha...

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Detalles Bibliográficos
Autores principales: Hutteau-Hamel, Tom, Mellouk, Amine, Trainel, Nicolas, Cassard, Anne-Marie, Bobé, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223416/
https://www.ncbi.nlm.nih.gov/pubmed/35743168
http://dx.doi.org/10.3390/ijms23126730