Blocking ERK-DAPK1 Axis Attenuates Glutamate Excitotoxicity in Epilepsy

Glutamate excitotoxicity induces neuronal cell death during epileptic seizures. Death-associated protein kinase 1 (DAPK1) expression is highly increased in the brains of epilepsy patients; however, the underlying mechanisms by which DAPK1 influences neuronal injury and its therapeutic effect on glut...

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Detalles Bibliográficos
Autores principales: Gan, Chen-Ling, Zou, Yulian, Chen, Dongmei, Shui, Xindong, Hu, Li, Li, Ruomeng, Zhang, Tao, Wang, Junhao, Mei, Yingxue, Wang, Long, Zhang, Mi, Tian, Yuan, Gu, Xi, Lee, Tae Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223430/
https://www.ncbi.nlm.nih.gov/pubmed/35742817
http://dx.doi.org/10.3390/ijms23126370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223430/
https://www.ncbi.nlm.nih.gov/pubmed/35742817
http://dx.doi.org/10.3390/ijms23126370

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