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Strain Typing of Classical Scrapie and Bovine Spongiform Encephalopathy (BSE) by Using Ovine PrP (ARQ/ARQ) Overexpressing Transgenic Mice

Transmissible spongiform encephalopathies (TSE), caused by abnormal prion protein (PrP(Sc)), affect many species. The most classical scrapie isolates harbor mixtures of strains in different proportions. While the characterization of isolates has evolved from using wild-type mice to transgenic mice,...

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Detalles Bibliográficos
Autores principales: Fatola, Olanrewaju I., Keller, Markus, Balkema-Buschmann, Anne, Olopade, James, Groschup, Martin H., Fast, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223460/
https://www.ncbi.nlm.nih.gov/pubmed/35743187
http://dx.doi.org/10.3390/ijms23126744