SOCS3 Ablation in Leptin Receptor-Expressing Cells Causes Autonomic and Cardiac Dysfunctions in Middle-Aged Mice despite Improving Energy and Glucose Metabolism

Leptin resistance is a hallmark of obesity. Treatments aiming to improve leptin sensitivity are considered a promising therapeutical approach against obesity. However, leptin receptor (LepR) signaling also modulates several neurovegetative aspects, such as the cardiovascular system and hepatic gluco...

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Detalles Bibliográficos
Autores principales: Pedroso, João A. B., da Silva, Ivson B., Zampieri, Thais T., Totola, Leonardo T., Moreira, Thiago S., Taniguti, Ana P. T., Diniz, Gabriela P., Barreto-Chaves, Maria Luiza M., Donato, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223472/
https://www.ncbi.nlm.nih.gov/pubmed/35742928
http://dx.doi.org/10.3390/ijms23126484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223472/
https://www.ncbi.nlm.nih.gov/pubmed/35742928
http://dx.doi.org/10.3390/ijms23126484

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