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SOCS3 Ablation in Leptin Receptor-Expressing Cells Causes Autonomic and Cardiac Dysfunctions in Middle-Aged Mice despite Improving Energy and Glucose Metabolism

Leptin resistance is a hallmark of obesity. Treatments aiming to improve leptin sensitivity are considered a promising therapeutical approach against obesity. However, leptin receptor (LepR) signaling also modulates several neurovegetative aspects, such as the cardiovascular system and hepatic gluco...

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Detalles Bibliográficos
Autores principales:	Pedroso, João A. B., da Silva, Ivson B., Zampieri, Thais T., Totola, Leonardo T., Moreira, Thiago S., Taniguti, Ana P. T., Diniz, Gabriela P., Barreto-Chaves, Maria Luiza M., Donato, Jose
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223472/ https://www.ncbi.nlm.nih.gov/pubmed/35742928 http://dx.doi.org/10.3390/ijms23126484

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