Dysregulated Brain Protein Phosphorylation Linked to Increased Human Tau Expression in the hTau Transgenic Mouse Model

Altered protein phosphorylation is a major pathologic modification in tauopathies and Alzheimer’s disease (AD) linked to abnormal tau fibrillar deposits in neurofibrillary tangles (NFTs) and pre-tangles and β-amyloid deposits in AD. hTau transgenic mice, which express 3R and less 4R human tau with n...

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Detalles Bibliográficos
Autores principales: Ferrer, Isidro, Andrés-Benito, Pol, Ausín, Karina, Cartas-Cejudo, Paz, Lachén-Montes, Mercedes, del Rio, José Antonio, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223516/
https://www.ncbi.nlm.nih.gov/pubmed/35742871
http://dx.doi.org/10.3390/ijms23126427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223516/
https://www.ncbi.nlm.nih.gov/pubmed/35742871
http://dx.doi.org/10.3390/ijms23126427

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