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Dual-Hit Model of Parkinson’s Disease: Impact of Dysbiosis on 6-Hydroxydopamine-Insulted Mice—Neuroprotective and Anti-Inflammatory Effects of Butyrate

Recent evidence highlights Parkinson’s disease (PD) initiation in the gut as the prodromal phase of neurodegeneration. Gut impairment due to microbial dysbiosis could affect PD pathogenesis and progression. Here, we propose a two-hit model of PD through ceftriaxone (CFX)-induced dysbiosis and gut in...

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Detalles Bibliográficos
Autores principales: Avagliano, Carmen, Coretti, Lorena, Lama, Adriano, Pirozzi, Claudio, De Caro, Carmen, De Biase, Davide, Turco, Luigia, Mollica, Maria Pina, Paciello, Orlando, Calignano, Antonio, Meli, Rosaria, Lembo, Francesca, Mattace Raso, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223521/
https://www.ncbi.nlm.nih.gov/pubmed/35742813
http://dx.doi.org/10.3390/ijms23126367