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High-Mobility Group Box 1 Inhibitor BoxA Alleviates Neuroinflammation-Induced Retinal Ganglion Cell Damage in Traumatic Optic Neuropathy

Traumatic optic neuropathy (TON) is a significant cause of vision loss and irreversible blindness worldwide. It is defined as retinal ganglion cell death and axon degeneration caused by injury. Optic nerve crush (ONC), a well-validated model of TON, activates retinal microglia and initiates neuroinf...

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Detalles Bibliográficos
Autores principales: Peng, Jingyi, Jin, Jiayi, Su, Wenru, Shao, Wanwen, Li, Weihua, Li, Zhiquan, Yu, Huan, Zheng, Yongxin, Zhong, Liuxueying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223527/
https://www.ncbi.nlm.nih.gov/pubmed/35743157
http://dx.doi.org/10.3390/ijms23126715