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High-Mobility Group Box 1 Inhibitor BoxA Alleviates Neuroinflammation-Induced Retinal Ganglion Cell Damage in Traumatic Optic Neuropathy
Traumatic optic neuropathy (TON) is a significant cause of vision loss and irreversible blindness worldwide. It is defined as retinal ganglion cell death and axon degeneration caused by injury. Optic nerve crush (ONC), a well-validated model of TON, activates retinal microglia and initiates neuroinf...
Autori principali: | , , , , , , , , |
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Natura: | Online Articolo testo |
Lingua: | English |
Pubblicazione: |
MDPI
2022
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Soggetti: | |
Accesso online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223527/ https://www.ncbi.nlm.nih.gov/pubmed/35743157 http://dx.doi.org/10.3390/ijms23126715 |