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DMT1 Protects Macrophages from Salmonella Infection by Controlling Cellular Iron Turnover and Lipocalin 2 Expression

Macrophages are at the center of innate pathogen control and iron recycling. Divalent metal transporter 1 (DMT1) is essential for the uptake of non-transferrin-bound iron (NTBI) into macrophages and for the transfer of transferrin-bound iron from the endosome to the cytoplasm. As the control of cell...

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Detalles Bibliográficos
Autores principales: Grander, Manuel, Hoffmann, Alexander, Seifert, Markus, Demetz, Egon, Grubwieser, Philipp, Pfeifhofer-Obermair, Christa, Haschka, David, Weiss, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223531/
https://www.ncbi.nlm.nih.gov/pubmed/35743233
http://dx.doi.org/10.3390/ijms23126789