5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence Imaging for Tumor Detection: Recent Advances and Challenges

5-Aminolevulinic acid (5-ALA) is a natural amino acid and a precursor of heme and chlorophyll. Exogenously administered 5-ALA is metabolized into protoporphyrin IX (PpIX). PpIX accumulates in cancer cells because of the low activity of ferrochelatase, an enzyme that metabolizes PpIX to heme. High ex...

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Detalles Bibliográficos
Autores principales: Harada, Yoshinori, Murayama, Yasutoshi, Takamatsu, Tetsuro, Otsuji, Eigo, Tanaka, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223645/
https://www.ncbi.nlm.nih.gov/pubmed/35742921
http://dx.doi.org/10.3390/ijms23126478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223645/
https://www.ncbi.nlm.nih.gov/pubmed/35742921
http://dx.doi.org/10.3390/ijms23126478

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