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5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence Imaging for Tumor Detection: Recent Advances and Challenges

5-Aminolevulinic acid (5-ALA) is a natural amino acid and a precursor of heme and chlorophyll. Exogenously administered 5-ALA is metabolized into protoporphyrin IX (PpIX). PpIX accumulates in cancer cells because of the low activity of ferrochelatase, an enzyme that metabolizes PpIX to heme. High ex...

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Detalles Bibliográficos
Autores principales:	Harada, Yoshinori, Murayama, Yasutoshi, Takamatsu, Tetsuro, Otsuji, Eigo, Tanaka, Hideo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223645/ https://www.ncbi.nlm.nih.gov/pubmed/35742921 http://dx.doi.org/10.3390/ijms23126478

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