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Cytoplasmic p53β Isoforms Are Associated with Worse Disease-Free Survival in Breast Cancer

TP53 mutations are associated with tumour progression, resistance to therapy and poor prognosis. However, in breast cancer, TP53′s overall mutation frequency is lower than expected (~25%), suggesting that other mechanisms may be responsible for the disruption of this critical tumour suppressor. p53...

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Detalles Bibliográficos
Autores principales: Steffens Reinhardt, Luiza, Groen, Kira, Morten, Brianna C., Bourdon, Jean-Christophe, Avery-Kiejda, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223648/
https://www.ncbi.nlm.nih.gov/pubmed/35743117
http://dx.doi.org/10.3390/ijms23126670