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Cytoplasmic p53β Isoforms Are Associated with Worse Disease-Free Survival in Breast Cancer
TP53 mutations are associated with tumour progression, resistance to therapy and poor prognosis. However, in breast cancer, TP53′s overall mutation frequency is lower than expected (~25%), suggesting that other mechanisms may be responsible for the disruption of this critical tumour suppressor. p53...
Autores principales: | Steffens Reinhardt, Luiza, Groen, Kira, Morten, Brianna C., Bourdon, Jean-Christophe, Avery-Kiejda, Kelly A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223648/ https://www.ncbi.nlm.nih.gov/pubmed/35743117 http://dx.doi.org/10.3390/ijms23126670 |
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