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Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human Ovarian Cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesenchymal Transition Pathways

Ovarian cancer (OC) ranks first in cancer-related deaths out of all female reproductive malignancies with high-pitched tumor relapse and chemoresistance. Several reports correlate cancer occurrences with exposure to xenobiotics via induction of a protein receptor named aryl hydrocarbon receptor (AhR...

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Detalles Bibliográficos
Autores principales: Therachiyil, Lubna, Krishnankutty, Roopesh, Ahmad, Fareed, Mateo, Jericha M., Uddin, Shahab, Korashy, Hesham M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223661/
https://www.ncbi.nlm.nih.gov/pubmed/35742838
http://dx.doi.org/10.3390/ijms23126395