Kinase Activity of PAR1b, Which Mediates Nuclear Translocation of the BRCA1 Tumor Suppressor, Is Potentiated by Nucleic Acid-Mediated PAR1b Multimerization

PAR1b is a cytoplasmic serine/threonine kinase that controls cell polarity and cell–cell interaction by regulating microtubule stability while mediating cytoplasmic-to-nuclear translocation of BRCA1. PAR1b is also a cellular target of the CagA protein of Helicobacter pylori, which leads to chronic i...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishikawa, Hiroko, Christiany, Priscillia, Hayashi, Takeru, Iizasa, Hisashi, Yoshiyama, Hironori, Hatakeyama, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223676/
https://www.ncbi.nlm.nih.gov/pubmed/35743080
http://dx.doi.org/10.3390/ijms23126634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223676/
https://www.ncbi.nlm.nih.gov/pubmed/35743080
http://dx.doi.org/10.3390/ijms23126634

Ejemplares similares