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Cancer Malignancy Is Correlated with Upregulation of PCYT2-Mediated Glycerol Phosphate Modification of α-Dystroglycan

The dystrophin–glycoprotein complex connects the cytoskeleton with base membrane components such as laminin through unique O-glycans displayed on α-dystroglycan (α-DG). Genetic impairment of elongation of these glycans causes congenital muscular dystrophies. We previously identified that glycerol ph...

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Detalles Bibliográficos
Autores principales: Umezawa, Fumiko, Natsume, Makoto, Fukusada, Shigeki, Nakajima, Kazuki, Yamasaki, Fumiya, Kawashima, Hiroto, Kuo, Chu-Wei, Khoo, Kay-Hooi, Shimura, Takaya, Yagi, Hirokazu, Kato, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223686/
https://www.ncbi.nlm.nih.gov/pubmed/35743105
http://dx.doi.org/10.3390/ijms23126662