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SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway

Nonalcoholic fatty liver disease (NAFLD), a condition strongly associated with obesity and insulin resistance, is characterized by hepatic lipid accumulation and activation of the endoplasmic reticulum (ER) stress response. The sirtuin 2 (SIRT2) protein deacetylase is emerging as a new player in met...

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Detalles Bibliográficos
Autores principales: Leal, Helena, Cardoso, João, Valério, Patrícia, Quatorze, Marta, Carmona, Vítor, Cunha-Santos, Janete, Pereira de Almeida, Luís, Pereira, Cláudia, Cavadas, Cláudia, Gomes, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223775/
https://www.ncbi.nlm.nih.gov/pubmed/35743232
http://dx.doi.org/10.3390/ijms23126790