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SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway
Nonalcoholic fatty liver disease (NAFLD), a condition strongly associated with obesity and insulin resistance, is characterized by hepatic lipid accumulation and activation of the endoplasmic reticulum (ER) stress response. The sirtuin 2 (SIRT2) protein deacetylase is emerging as a new player in met...
Autores principales: | Leal, Helena, Cardoso, João, Valério, Patrícia, Quatorze, Marta, Carmona, Vítor, Cunha-Santos, Janete, Pereira de Almeida, Luís, Pereira, Cláudia, Cavadas, Cláudia, Gomes, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223775/ https://www.ncbi.nlm.nih.gov/pubmed/35743232 http://dx.doi.org/10.3390/ijms23126790 |
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