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γH2AX, a DNA Double-Strand Break Marker, Correlates with PD-L1 Expression in Smoking-Related Lung Adenocarcinoma

In recent years, the choice of immune checkpoint inhibitors (ICIs) as a treatment based on high expression of programmed death-ligand 1 (PD-L1) in lung cancers has been increasing in prevalence. The high expression of PD-L1 could be a predictor of ICI efficacy as well as high tumor mutation burden (...

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Detalles Bibliográficos
Autores principales: Sakurai, Eiko, Ishizawa, Hisato, Kiriyama, Yuka, Michiba, Ayano, Hoshikawa, Yasushi, Tsukamoto, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223793/
https://www.ncbi.nlm.nih.gov/pubmed/35743122
http://dx.doi.org/10.3390/ijms23126679