Comparative Assessment of the Structural Features of Originator Recombinant Human Follitropin Alfa Versus Recombinant Human Follitropin Alfa Biosimilar Preparations Approved in Non-European Regions

Although the full primary structures of the alfa and beta subunits of reference r-hFSH-alfa and its biosimilars are identical, cell context-dependent differences in the expressing cell lines and manufacturing process can lead to variations in glycosylation profiles. In the present study, we compared...

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Detalles Bibliográficos
Autores principales: Manzi, Lucio, Sepe, Nunzio, Migliaccio, Walter, Lanzoni, Ludovica, Iozzino, Luisa, D’Angelo, Fabrizia, Colarusso, Lucia, Montenegro, Susana, Palmese, Angelo, D’Hooghe, Thomas, Ulloa-Aguirre, Alfredo, Koloda, Yulia, Lispi, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223809/
https://www.ncbi.nlm.nih.gov/pubmed/35743204
http://dx.doi.org/10.3390/ijms23126762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223809/
https://www.ncbi.nlm.nih.gov/pubmed/35743204
http://dx.doi.org/10.3390/ijms23126762

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