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Hepatic Macrophage Abundance and Phenotype in Aging and Liver Iron Accumulation

Liver macrophages serve important roles in iron homeostasis through phagocytosis of effete erythrocytes and the export of iron into the circulation. Conversely, intracellular iron can alter macrophage phenotype. Aging increases hepatic macrophage number and nonparenchymal iron, yet it is unknown whe...

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Detalles Bibliográficos
Autor principal: Bloomer, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223835/
https://www.ncbi.nlm.nih.gov/pubmed/35742946
http://dx.doi.org/10.3390/ijms23126502