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Hepatic Macrophage Abundance and Phenotype in Aging and Liver Iron Accumulation
Liver macrophages serve important roles in iron homeostasis through phagocytosis of effete erythrocytes and the export of iron into the circulation. Conversely, intracellular iron can alter macrophage phenotype. Aging increases hepatic macrophage number and nonparenchymal iron, yet it is unknown whe...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223835/ https://www.ncbi.nlm.nih.gov/pubmed/35742946 http://dx.doi.org/10.3390/ijms23126502 |