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Determination of Intra- and Extracellular Metabolic Adaptations of 3D Cell Cultures upon Challenges in Real-Time by NMR

NMR flow devices provide longitudinal real-time quantitative metabolome characterisation of living cells. However, discrimination of intra- and extracellular contributions to the spectra represents a major challenge in metabolomic NMR studies. The present NMR study demonstrates the possibility to qu...

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Detalles Bibliográficos
Autores principales: Urzì, Christian, Hertig, Damian, Meyer, Christoph, Maddah, Sally, Nuoffer, Jean-Marc, Vermathen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223855/
https://www.ncbi.nlm.nih.gov/pubmed/35743000
http://dx.doi.org/10.3390/ijms23126555