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Synthesis and Anti-Cancer Activity of New Pyrazolinyl-Indole Derivatives: Pharmacophoric Interactions and Docking Studies for Identifying New EGFR Inhibitors
Newly designed series of indole-containing pyrazole analogs, pyrazolinylindoles, were synthesized, and their structures were confirmed based on the spectral data of the (1)H NMR, (13)C NMR, and HR-MS analyses. Preliminary anti-cancer activity testings were carried out by the National Cancer Institut...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223872/ https://www.ncbi.nlm.nih.gov/pubmed/35742992 http://dx.doi.org/10.3390/ijms23126548 |