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Synthesis and Anti-Cancer Activity of New Pyrazolinyl-Indole Derivatives: Pharmacophoric Interactions and Docking Studies for Identifying New EGFR Inhibitors

Newly designed series of indole-containing pyrazole analogs, pyrazolinylindoles, were synthesized, and their structures were confirmed based on the spectral data of the (1)H NMR, (13)C NMR, and HR-MS analyses. Preliminary anti-cancer activity testings were carried out by the National Cancer Institut...

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Detalles Bibliográficos
Autores principales: Khalilullah, Habibullah, Agarwal, Deepak K., Ahsan, Mohamed J., Jadav, Surender S., Mohammed, Hamdoon A., Khan, Masood Alam, Mohammed, Salman A. A., Khan, Riaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223872/
https://www.ncbi.nlm.nih.gov/pubmed/35742992
http://dx.doi.org/10.3390/ijms23126548