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A Cross-Tissue Investigation of Molecular Targets and Physiological Functions of Nsun6 Using Knockout Mice

The 5-methylcytosine (m5C) modification on an mRNA molecule is deposited by Nsun2 and its paralog Nsun6. While the physiological functions of Nsun2 have been carefully studied using gene knockout (KO) mice, the physiological functions of Nsun6 remain elusive. In this study, we generated an Nsun6-KO...

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Detalles Bibliográficos
Autores principales: Wang, Wen, Huang, Hengjun, Jiang, Hao, Tian, Chi, Tang, Yisen, Gan, Diwen, Wen, Xiaozhen, Song, Zhenyu, He, Yuhao, Ou, Xijun, Fang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224068/
https://www.ncbi.nlm.nih.gov/pubmed/35743028
http://dx.doi.org/10.3390/ijms23126584