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Structural and Functional Analysis of SHP Promoter and Its Transcriptional Response to FXR in Zn-Induced Changes to Lipid Metabolism

Zinc alleviates hepatic lipid deposition, but the transcriptional regulatory mechanisms are still unclear. In this study, we characterized the promoter of an SHP (short heterodimer partner) in a teleost Pelteobagrus fulvidraco. The binding sites of an FXR (farnesoid X receptor) were predicted by the...

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Detalles Bibliográficos
Autores principales: Gao, Han, Fan, Xing, Wu, Qi-Chun, Chen, Chuan, Xiao, Fei, Wu, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224202/
https://www.ncbi.nlm.nih.gov/pubmed/35742980
http://dx.doi.org/10.3390/ijms23126523