CRISPR/Cas9-Directed Gene Trap Constitutes a Selection System for Corrected BCR/ABL Leukemic Cells in CML

Chronic myeloid leukaemia (CML) is a haematological neoplasm driven by the BCR/ABL fusion oncogene. The monogenic aspect of the disease and the feasibility of ex vivo therapies in haematological disorders make CML an excellent candidate for gene therapy strategies. The ability to abolish any coding...

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Detalles Bibliográficos
Autores principales: Vuelta, Elena, Ordoñez, José L., Sanz, David J., Ballesteros, Sandra, Hernández-Rivas, Jesús M., Méndez-Sánchez, Lucía, Sánchez-Martín, Manuel, García-Tuñón, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224210/
https://www.ncbi.nlm.nih.gov/pubmed/35742831
http://dx.doi.org/10.3390/ijms23126386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224210/
https://www.ncbi.nlm.nih.gov/pubmed/35742831
http://dx.doi.org/10.3390/ijms23126386

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