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Extracellular Histones Trigger Disseminated Intravascular Coagulation by Lytic Cell Death

Histones are cationic nuclear proteins that are essential for the structure and functions of eukaryotic chromatin. However, extracellular histones trigger inflammatory responses and contribute to death in sepsis by unknown mechanisms. We recently reported that inflammasome activation and pyroptosis...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Wu, Congqing, Li, Lan, Pandeya, Ankit, Zhang, Guoying, Cui, Jian, Kirchhofer, Daniel, Wood, Jeremy P., Smyth, Susan S., Wei, Yinan, Li, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224270/
https://www.ncbi.nlm.nih.gov/pubmed/35743244
http://dx.doi.org/10.3390/ijms23126800