Chl1, an ATP-Dependent DNA Helicase, Inhibits DNA:RNA Hybrids Formation at DSB Sites to Maintain Genome Stability in S. pombe

As an ATP-dependent DNA helicase, human ChlR1/DDX11 (Chl1 in yeast) can unwind both DNA:RNA and DNA:DNA substrates in vitro. Studies have demonstrated that ChlR1 plays a vital role in preserving genome stability by participating in DNA repair and sister chromatid cohesion, whereas the ways in which...

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Detalles Bibliográficos
Autores principales: He, Deyun, Du, Zhen, Xu, Huiling, Bao, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224301/
https://www.ncbi.nlm.nih.gov/pubmed/35743069
http://dx.doi.org/10.3390/ijms23126631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224301/
https://www.ncbi.nlm.nih.gov/pubmed/35743069
http://dx.doi.org/10.3390/ijms23126631

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