DKK-1 Is Underexpressed in Mesenchymal Stem Cells from Patients with Ankylosing Spondylitis and Further Downregulated by IL-17

Dickkopf-1 (Dkk-1) is a key regulator of bone remodeling in spondyloarthropathies. Nevertheless, data regarding its expression in cells of pathophysiologic relevance, such as mesenchymal stem cells (MSCs), are lacking. Herein, we aimed to address DKK1 gene expression and Wnt pathway activation in MS...

Descripción completa

Detalles Bibliográficos
Autores principales: Daoussis, Dimitrios, Kanellou, Anastasia, Panagiotopoulos, Elias, Papachristou, Dionysios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224314/
https://www.ncbi.nlm.nih.gov/pubmed/35743102
http://dx.doi.org/10.3390/ijms23126660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224314/
https://www.ncbi.nlm.nih.gov/pubmed/35743102
http://dx.doi.org/10.3390/ijms23126660

Ejemplares similares