Expanded Potential of the Polyamine Analogue SBP-101 (Diethyl Dihydroxyhomospermine) as a Modulator of Polyamine Metabolism and Cancer Therapeutic

Naturally occurring polyamines are absolutely required for cellular growth and proliferation. Many neoplastic cells are reliant on elevated polyamine levels and maintain these levels through dysregulated polyamine metabolism. The modulation of polyamine metabolism is thus a promising avenue for canc...

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Detalles Bibliográficos
Autores principales: Holbert, Cassandra E., Foley, Jackson R., Murray Stewart, Tracy, Casero, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224330/
https://www.ncbi.nlm.nih.gov/pubmed/35743239
http://dx.doi.org/10.3390/ijms23126798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224330/
https://www.ncbi.nlm.nih.gov/pubmed/35743239
http://dx.doi.org/10.3390/ijms23126798

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