A Small Molecule That Promotes Cellular Senescence Prevents Fibrogenesis and Tumorigenesis

Uncontrolled proliferative diseases, such as fibrosis or cancer, can be fatal. We previously found that a compound containing the chromone scaffold (CS), ONG41008, had potent antifibrogenic effects associated with EMT or cell-cycle control resembling tumorigenesis. We investigated the effects of ONG...

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Detalles Bibliográficos
Autores principales: Meang, Moon Kee, Kim, Saesbyeol, Kim, Ik-Hwan, Kim, Han-Soo, Youn, Byung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224374/
https://www.ncbi.nlm.nih.gov/pubmed/35743290
http://dx.doi.org/10.3390/ijms23126852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224374/
https://www.ncbi.nlm.nih.gov/pubmed/35743290
http://dx.doi.org/10.3390/ijms23126852

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