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A Small Molecule That Promotes Cellular Senescence Prevents Fibrogenesis and Tumorigenesis
Uncontrolled proliferative diseases, such as fibrosis or cancer, can be fatal. We previously found that a compound containing the chromone scaffold (CS), ONG41008, had potent antifibrogenic effects associated with EMT or cell-cycle control resembling tumorigenesis. We investigated the effects of ONG...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224374/ https://www.ncbi.nlm.nih.gov/pubmed/35743290 http://dx.doi.org/10.3390/ijms23126852 |