CX3CL1 Action on Microglia Protects from Diet-Induced Obesity by Restoring POMC Neuronal Excitability and Melanocortin System Activity Impaired by High-Fat Diet Feeding

Both hypothalamic microglial inflammation and melanocortin pathway dysfunction contribute to diet-induced obesity (DIO) pathogenesis. Previous studies involving models of altered microglial signaling demonstrate altered DIO susceptibility with corresponding POMC neuron cytological changes, suggestin...

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Detalles Bibliográficos
Autores principales: Banerjee, Jineta, Dorfman, Mauricio D., Fasnacht, Rachael, Douglass, John D., Wyse-Jackson, Alice C., Barria, Andres, Thaler, Joshua P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224384/
https://www.ncbi.nlm.nih.gov/pubmed/35742824
http://dx.doi.org/10.3390/ijms23126380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224384/
https://www.ncbi.nlm.nih.gov/pubmed/35742824
http://dx.doi.org/10.3390/ijms23126380

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